University of Liverpool Led Preclinical Research Indicates Thapsigargin Powerful Antiviral Impact on SARS-CoV-2

University of Liverpool Led Preclinical Research Indicates Thapsigargin Powerful Antiviral Impact on SARS-CoV-2

Based on preclinical research in cell cultures and animals, a team of investigators at the University of Nottingham in England and collaborators find that thapsigargin, a promising broad spectrum antiviral is actually highly effective against SARS-CoV-2, the virus behind COVID-19, the common cold coronavirus, repository syncytial virus (RSV) and the influenza A virus. Could the novel antiviral property of this substance derived from a western Mediterranean plant represent major implications in how future epidemics and pandemics, including the current one, are managed?

TrialSite provides a brief breakdown of the current University of Nottingham findings that were recently published in the journal Viruses.

Who is behind this study?

The study represents a collaborative project led by Professor Kin-Chow Chang as well as experts from the University of Nottingham (Schools of Veterinary Medicine and Sciences, Biosciences, Pharmacy, Medicine and Chemistry), and colleagues at the Animal and Plant Health Agency (APHA), China Agricultural University and Pirbright Institute).

What is thapsigargin?

Classified as a “sesquiterpene lactone,” it’s extracted from the plant ...

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