The University of Chicago will assume the lead for the NRG Oncology Statistics and Data Management Center (SDMC). This initiative is receiving six more years of National Cancer Institute (NCI) funding. Michelle Le Beau, PhD, director of the University of Chicago Medicine Comprehensive Cancer Center, notes “we are delighted that our institution is providing leadership on coordinating clinical trials that have the potential to improve the standard of care for any types of cancers.” NRG Oncology is the largest of five groups that comprise the NCI’s National Clinical Trials Network (NCTN). Each group has a separate and distinct Operations Center and Statistics and Data Management Center. The SDMCs are responsible for trial design and development in collaboration with investigators, data management, trial safety and efficacy monitoring, and auditing and quality control, in addition to collaborating on the larger research agenda of the group. SDMCs partner closely with their respective Operations Center, which consists of group leadership for the clinical and scientific research agenda, and is responsible for developing new protocols and managing the regulatory, financial and membership committees as well as the disease site and other scientific committees.
A team of approximately 80 SDMC members based at the University of Chicago, American College of Radiology, University of Pittsburgh and Roswell Park Cancer Institute will be responsible for all aspects of NRG Oncology multicenter studies that accrue patients from more than 1,800 sites in North America, including the University of Chicago Medicine Comprehensive Cancer Center, and selected participating institutions around the world.