UMass Lowell PI Secures $2.7m: Embrace of AI to Investigate How Alzheimer’s Disease Evolves

A UMass Lowell researchers received $2.7 million to investigate just how Alzheimer’s disease actually evolves. Funded by the NIH’s National Institute on Aging, Electrical, and Computer Engineering Associate Prof. Joyita Dutta aims to develop models that predict the progression of tau tangles in the brain. While tau is an important protein that helps stabilize the brain’s nerve cells, in cases of Alzheimer’s, an abnormal form of tau builds ups inside the nerve cells and evolves into tangles. Along with amyloid plaques, which are abnormal proteins that build up between the nerve cells, tau tangles are primary markers for Alzheimer’s disease. Dutta is the sole research for this five-year award.

Alzheimer’s Disease Crisis

While the causes of Alzheimer’s are not fully understood, the number of people affected by the disease continues to grow. According to the Centers for Disease Control, in 2020, as many as 5.8 million Americans were living with Alzheimer’s. That number is projected to rise to 14 million by 2060. There is currently no known cure for the disease, but research indicates that early diagnosis is key to treating it.

AI for a ’Network’ Perspective

Dutta directs U...

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