The Diabetic Foot Consortium: The First U.S. TrialSite Network to Study Diabetic Foot Ulcers: A $13B per year Problem

The Diabetic Foot Consortium: The First U.S. TrialSite Network to Study Diabetic Foot Ulcers: A $13B per year Problem

Thanks to money from the National Institutes of Health (NIH), Six U.S. research centers have come together to form the first-ever multicenter network to study diabetic foot ulcers, a common and burdensome complication of diabetes and the leading cause of lower-limb amputations in the United States. Called the Diabetic Foot Consortium (DFC), the TrialSite network seeks to lay the foundation for a clinical trial network to investigate how to improve diabetic wound healing and prevent amputations among the 27 million American adults with diabetes. The DFC is supported by the NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

The TrialSite provides a breakdown of this new trial site network.

What is the fundamental health challenge here?

Up to 34% of people with diabetes will develop a foot ulcer in their lifetime, and half of the foot ulcers become infected. Each year, about 100,000 Americans with diabetes will lose part of their lower limb because a foot ulcer becomes infected or does not heal. 

“For people with diabetes, foot ulcers can be devastating and lead to even more devastating amputation. They affect quality of life an...

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