Texas A&M University Researcher-Originated Anti-Fibrotic Agent Acquired by Swiss Giant for $1B

Clinical Trials Lead to New Standard of Care for Lung Cancer Patients

Roche acquired a U.S. biotech that moves to the last clinical trial stages with a drug addressing idiopathic pulmonary fibrosis. The deal to acquire Promedior totals up to $1.4 billion including a down payment of $390 million plus up to $1 billion potential if several other conditions are met. The prized asset? PRM-151, which is said to be superior to other IPF therapies. Roche’s IPF therapy Esbriet brought just over $1billion in 2018. Promedior originated out of research from professors at Texas A&M University.

What is IPF?

A type of chronic scarring lung disease which is associated with a progressive and irreversible decline in lung function. The cause is unknown. Often the symptoms include a dry cough and shortness of breath. Risk factors can include smoking, select viral infections and a family history of the condition. A scarring of the lungs represents the underlying mechanism of the disease. Diagnosis involves ruling out other possible conditions. It is a type of interstitial lung disease (ILD). Average life expectancy after diagnosis is 4 years.

Frequency of Disease

About 5 million globally. The disease occurs at about a rate of 12 per 100,000 per year. The...

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