St. Jude Identifies Method to Reduce Risk of Brain Damage in Leukemia Survivors

TrialsiteN

MDLinx reports that children with acute lymphoblastic leukemia (ALL) are at an extremely high risk of sepsis compared to the general population. In the first-published study of its kind, St. Jude Children’s Research Hospital scientists have discovered a link between sepsis during cancer treatment and long-term neurocognitive dysfunction. Sepsis is a potentially life-threatening condition in which the body wages a massive immune response to a bacterial infection of the blood. The study revealed survivors with a history of sepsis performed worse than other participants on tests measuring multiple neurocognitive domains, including executive function and attention span.

Lead Research/Investigators

Josh Wolf, MBBS

Kevin Krull, PhD