Spanish Research Center Launches Ivermectin Clinical Trial Targeting Mild COVID-19 Patients

Spanish Research Center & Provider Launch Ivermectin Clinical Trial Targeting Mild COVID-19 Patients

Clinical Universidad de Navarra and the Barcelona Institute for Global Health (ISGlobal), a center supported by "la Caixa” Foundation, have launched a clinical trial to investigate the efficacy of ivermectin against COVID-19. The study team will combine ivermectin with Idilfarma to determine whether administration of ivermectin is associated with a shorter clearance time.

Background

Ivermectin was recently evidenced to inhibit the replication of SARS-CoV-2 in vitro at very high doses (Monash University, Australia), but this effect is now being tested in a number of studies from Johns Hopkins University to University of Kentucky in the United States, Tanta University in Egypt, as well as centers in Argentina and Iraq.  

The Study

Titled the SARS-CoV-2 Ivermectin Navarra ISGlobal Trial (SAINT), the Spanish study’s investigators will probe with a randomized trial with 24 participants with mild cases of COVID-19 and no risk factors receiving a single oral dose of ivermectin or placebo less than 48 hours after the onset of the symptoms.

In the study, the newly diagnosed patients don’t require hospitalization, so follow-up is carried out in their homes during their period...

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