Scripps’ Disney Lab Breakthrough RNA-Targeting Compounds Dismantle COVID-19’s ‘Clutch’ via Disabling Reproduction Engine

Scripps’ Disney Lab Breakthrough RNA-Targeting Compounds Dismantle COVID-19’s ‘Clutch’ via Disabling Reproduction Engine

Research rockstar Matthew Disney, PhD, and team from Scripps Florida have created drug-like compounds that based on results thus far in human cell studies, actually bind and destroy the “frameshifting element” associated with SARS-CoV-2, the virus behind COVID-19, hence inhibiting the virus from replication. The Scripps team in Jupiter, Florida, managed to engineer RNA-targeting compounds that disable this replication engine, a sort of “clutch-like device” that SARS-CoV-2 requires to produce replicates of itself once it enters cells. As Professor Disney emphasized in a recent Scripps press release, their compound stops the SARS-CoV-2 pathogen from actually shifting gears and thereby stops the disease in its tracks. The Scripps Research team in Jupiter means real business for this part of Florida—producing $3 billion worth of economic activity for the region in just the last 15 years. 

Brief Overview

Scripps explained in their recent press release that viruses such as COVID-19 enter the human cell and use that cell’s protein-production machinery to generate replicates of the virus. Of course, these are infectious and only serve to make the virus spread and the individual pote...

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