Polyethylene Glycol, not S-Protein Biogenesis, May Account for Ultralow and Waning Efficacy of COVID-19 mRNA Vaccines

Polyethylene Glycol, not S-Protein Biogenesis, May Account for Ultralow and Waning Efficacy of COVID-19 mRNA Vaccines

Note that views expressed in this opinion article are the writer’s personal views and not necessarily those of TrialSite.

Dr. Ron Brown – Opinion Editorial

October 6, 2021

The reported efficacy of the COVID-19 mRNA vaccines is in the range of 95%. But vaccine efficacy, or relative risk reduction, doesn’t tell the whole story of the mRNA vaccines. An analysis of clinical trial data shows that the absolute risk reduction of the mRNA vaccines is in the ultralow range of 1%, but that information is not being disseminated to the public; Outcome Reporting Bias in COVID-19 mRNA Vaccines. These unreported clinical trial results do not appear to support ribosomal translation and biogenesis of SARS-CoV-2 S proteins from the genetic sequence of injected mRNA—a hypothetical mechanism to stimulate immunogenicity against the virus. Rather, the ultralow immune response of the vaccines may be due largely to added ingredients. For example, polyethylene glycol (PEG) is added to the COVID-19 mRNA vaccines as a stabilizer, but PEG also has immunosuppressant and anti-inflammatory effects; PEG potential adjuvant treatment for COVID-19; Polyethylene glycol in sepsis; Polyethylene glycol and Inf...

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