Greek Pharmacology Investigation: mRNA COVID-19 Vaccine Adverse Event Possible Molecular Mechanisms

Published at the start of the year in Springer Link,  Malamatenia Lamprinou,  a pharmacologist at Aristotle University of Thessaloniki, School of Medicine, Laboratory of Clinical Pharmacology,  and colleagues review the literature associated with COVID-19 vaccines with an eye on the potential mechanisms of action associated with rare serious adverse events including include allergic and anaphylactic reactions, thrombosis and thrombocytopenia, myocarditis, Bell&rsquo;s palsy, transient myelitis, Guillen-Barre syndrome, recurrences of herpes-zoster, autoimmunity flares, epilepsy, and tachycardia. What are the potential molecular mechanisms associated with these rare adverse events of interest? What are any trends or patterns by vaccine components and platforms?
It&rsquo;s important to note that Lamprinou and colleagues stress that all COVID-19 vaccines in the market at the point of writing maintain an acceptable safety record. Would this be the case without the declared health emergency?