In an effort to discover new treatments for brain tumors, such as glioblastoma, the prominent neurology-focused trial site Ivy Brain Tumor Center at Barrow Neurological Institute with participation including St. Joseph's Hospital and Medical Center launched a ground-breaking Phase 0 clinical trial evaluating a new experimental drug delivery method called superselective intra-arterial infusion, or SSIAI. In a small study that will involve 12 subjects with recurrent, high-grade glioma in the frontal or temporal lobes, the Arizona-based investigators will use the novel technique to deliver a highly-concentrated dose of experimental drug directly to the brain tumor while minimizing systemic side effects. An investigator-led study by Nader Sanai, M.D., Director of the Ivy Brain Tumor Center and Director of Neurosurgical Oncology at Barrow Neurological Institute.
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