Researchers from Leicester Biomedical Research Centres (BIRCs), University of Leicester and National Institute for Health Research (NIHR) Nottingham and the University of Nottingham have examined genetic data of people who have moderate to severe asthma and European ancestry. The study involved a comparative study of over 10,000 people suffering from asthma and 50,000 people with normal lung function. The findings revealed new genetic variants linked to moderate-to-severe asthma and their sensitivity toward development of this condition.
Discovering the latent genetic origins of the disease gives scientists a renewed hope for improved treatment of this uncontrollable condition by targeting these genes with advanced therapies.
“Asthma is a fairly common but notoriously difficult disease to diagnose, treat and manage,” said Professor Ian Sayers, from University of Nottingham and NIHR Nottingham BRC.
Ian Sayers, from University of Nottingham and NIHR Nottingham BRC.