More Indicators That One Vaccine Dose Could Meet Societal Needs While Reducing Safety Signal

More Indicators That One Vaccine Dose Could Meet Societal Needs While Reducing Safety Signal

A recent study from Scotland reveals that one (1) dose of the COVID-19 vaccine confers roughly the same protection as two (2) doses when measuring the efficacy after allowing for a similar amount of time for immunity to develop.  TrialSite’s been on the record that in the case of the mRNA-based vaccine,s perhaps Board Room revenue decision making trumped healthcare. In a recent correspondence piece in The Lancet, the authors share, "Overall, a strong vaccine effect did not clearly manifest until at least 28 days after the first vaccine dose (HR 0·32, 95% CI 0·22–0·46; appendix p 3). Among S gene-negative cases, the effect of vaccination (at least 28 days after first or second dose) was to reduce the risk of hospital admission (HR 0·28, 95% CI 0·18–0·43) compared to unvaccinated."

Herein, the authors fail to state exactly what measure of vaccine effect they are quoting for the single dose. Are they referring to symptomatic infection, hospitalization, or other? However, when probing the Supplemental document, one can read the details more clearly. Refer to Table S2 where the authors list the hazard ratios for various dosing regimens and time offsets. ...

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