Meta-Analysis of Clinical Trials Links Omega-3 Fish Oils with Lower Risk of Cardiovascular Disease

Published online in the Journal of the American Heart Association, a new meta-analysis from Harvard T.H. Chan School of Public Health and Brigham and Women’s Hospital shows that people who received omega-3 fish oil supplements in randomized clinical trials had lower risks of heart attack and other cardiovascular disease (CVD) events compared with those who were given placebo.

Although researchers found an association between daily omega-3 supplementation and reduced risk of most CVD outcomes, including heart attack, death from coronary heart disease, and death from CVD, they did not see benefit for stroke. They did, however, notice that higher doses of omega-3 fish oil supplements appeared to provide even greater risk reductions.

The Author’s Analysis

Previous clinical trials of omega-3’s and CVD risks have been inconsistent and unclear. Now, though, according to first author Yang Hu, a postdoctoral fellow in the Department of Nutrition at Harvard Chan School: “This meta-analysis provides the most up-to-date evidence regarding the effects of omega-3 supplementation on risk of multiple CVD outcomes. We found significant protective effects of daily omega-3 supplementation agains...

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