Medical Genome Reference Bank Uses Whole-Genome Sequencing for Powerful Aging Database

Dark Daily reports on a genomic dataset that may provide useful diagnostic insights that can be used by clinical laboratory and pathology professionals to learn how and why some people age with good health.

The Medical Genome Reference Bank (MGRB) came about as a result of a collaboration between the following organizations:

  • Garvan Institute of Medical Research, University of New South Wales (UNSW)
  • Monash University

This new genetic database uses whole-genome sequencing (WGS) to answer important questions in many ways that could benefit medical laboratories.

With rapidly changing demographics, including a growing elderly population across the developed world, there is significant interest in ways to keep seniors in good health. The article posits that the development of effective lab testing services in support of improved of senior health represents a major opportunity for clinical laboratories, etc.

At the same time, genetics researchers are using WGS to discover new causes for many chronic Illnesses.  Moreover powerful new ways to diagnose diseases are coming online. Through its use of WGS, the MGRB now includes a huge database of thousands of healthy elderly people. The data it contains may enable pathology scientists to learn, from a genetic standpoint, why some people age well and others do not.

The research team published their work titled as “The Medical Genome Reference Bank: A Whole-Genome Data Resource of 4,000 Healthy Elderly Individuals. Rationale and Cohort Design” published in The European Journal of Human Ethics.