MATH+ Protocol Includes Ivermectin Option for Prophylaxis and Early Treatment of COVID-19; Phase of Disease Key to Care

MATH+ Protocol Includes Ivermectin Option for Prophylaxis and Early Treatment of COVID-19; Phase of Disease Key to Care

“MATH+” is the COVID-19 protocol by Dr. Paul Marik and the Front Line Covid-19 Critical Care Alliance (FLCCC), as previously reported by TrialSite. And while NIH is still recommending ivermectin be used only in clinical trials, the September 28 update to MATH+ includes this drug as described below. The protocol notes that it, “is our recommended approach to COVID-19 based on the best (and most recent) literature. This is a very dynamic situation; therefore, we will be updating the guideline as new information emerges.” Beginning with prophylaxis, or prevention, the protocol notes that a safe and effective “cocktail” of substances may prevent or mitigate COVID-19. For this purpose, Marik recommends melatonin, high-dose vitamin D3 (deficiency of which has been tied to increased risk of catching COVID-19 and worse outcomes), vitamin C, zinc, and famotidine. For post-exposure prophylaxis, home-treatment during the acute phase, and mildly symptomatic hospital patients, ivermectin is listed as an optional medication.

The Phase Dictates the Approach

The MATH+ protocol emphasizes that COVID-19 has different phases requiring different approaches. For example, antivirals likely only h...

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