Major Trials Sponsored by UK Government Target At-Risk Immunocompromised Patients & Elderly in Nursing Homes

Major Trials Sponsored by UK Government Target At-Risk Immunocompromised Patients & Elderly in Nursing Homes

Recently, the United Kingdom (UK) government’s Department of Health and Social Care (DHSC) announced two clinical trials supported by up to £3.2 million ($4.4m) on what are considered “pioneering” treatments thought to possibly be able to stop the spread of SARS-CoV-2, the virus behind COVID-19. The targeted subject are the hundreds of thousands of clinically vulnerable people and home care residents. In one study called the PROTECT-V trial, the University of Cambridge will investigate drugs that may serve to prevent COVID-19 infection among immunocompromised groups while the second study, called PROTECT-CH, is led by the University of Nottingham and investigates treatments for reducing the transmission of COVID-19, as well as hopefully reduce the threat of serious illness for care home residents and staff. The trial sponsors acknowledge British scientists and taxpayers have already contributed to breakthrough studies showing the benefit of two drugs, including dexamethasone and tocilizumab, the later drug with mixed results, as many prominent studies demonstrate no benefit. The British government is on the record that the end of the pandemic will be introduced by not only vaccine...

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