London School of Hygiene Tropical Medicine Launches Major Ivermectin Study in The Gambia Focusing on COVID-19

London School of Hygiene Tropical Medicine Launches Major Ivermectin Study in The Gambia Focusing on COVID-19

The London School of Hygiene Tropical Medicine (LSHTM) founded in 1899, specializes in public health and tropical medicine and now pursues a significant adaptive clinical trial affording the study team the ability to change the investigational products should evidence on the benefits or harm of the intervention being trialed implicate a particular direction. In the case of this Phase 3 trial, the prominent investigational team, operating in the West African country of The Gambia investigates the impact of cheap and widely available investigational products starting with Ivermectin. Targeting 1,200 participants, the investigators from the LSHTM’s Medical Research Council (MRC) unit assess the impact of Ivermectin, an anti-parasite drug approved by the U.S. Food and Drug Administration and many regulatory bodies around the world, on the natural history of SARS-CoV-2 in two cohorts, including 1) those with mild or moderate pneumonia (Cohort 1) and 2) those with severe pneumonia (Cohort 2), via a randomization to non-identical placebo or intervention arm.  Led by the MRC Unit The Gambia at LSHTM, one of two research units established in sub-Saharan Africa by the Medical Rese...

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