Researchers in the Netherlands at the Center for Experimental Molecular Medicine at Amsterdam UMC recently revealed that a psychiatric drug currently widely available in the UK can trigger robust responses in gut-based stem cells actually making them more impervious to harm from mutant, cancerous-causing stem cells associated with the APC gene. In a preclinical animal-based study recently published in the journal Nature and funded by Worldwide Cancer Research, a UK-based charity, a commonly used psychiatric therapy may actually serve to prevent bowel cancer. Now thanks to this significant breakthrough, a clinical trial has commenced to determine the efficacy of the drug called lithium with patients that have a genetic mutation that exposes them to extremely high risks of bowel cancer during their lifetime unless a surgery removing the large bowel is conducted. Can lithium help protect a normal set of gut-based stem cells from the aggressive tendencies of the APC gene?
Known as Colorectal cancer, this cancer develops in the colon or rectum and causes over 550,000 deaths per year. With over 11 million incidences per annum worldwide, the disease is caused by a numb...
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