Large Retrospective Cohort Study in Israel Points to High Rates of Myocarditis Associated with Pfizer-BioNTech Vaccine

Another important study out of Israel may impact thinking about mRNA COVID-19 vaccine safety.  Published recently in the New England Journal of Medicine, the authors took advantage of 4.7 million patient records from Clalit Health Services, one of Israel’s largest health care organizations (HCO).  Representing 52% of the eastern Mediterranean nation’s population, the real-world retrospective, observational study’s implications cannot be ignored. Led by top cardiologist Dr. Guy Witberg affiliated with Rabin Medical Center, Beilinson Hospital in Petah Tikva, the study centered on the Pfizer-BioNTech mRNA vaccine—BNT162b2. In America, the Food and Drug Administration (FDA) has issued a warning that while rare, some young people, especially males, face some risk of myocarditis and pericarditis. The U.S. Centers for Disease Control (CDC) estimates the population-wide incidence to be .48 cases of post-vaccination myocarditis per 100,000, persons, but the Israel-based study indicates the population-wide incidence to be 2.13 cases per 100,000 persons, or more than 4x higher.Dr. Witberg and the study team report an even higher incidence for the male cohort of 16 to 29 year olds: Males in t...

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