Kaiser Permanente Study Reveals Long-Term use of Bladder Drug Elmiron Linked to Retinal Damage

Bladder drug Elmiron linked to retinal damage according to new research by Kaiser Permanente Northern California.
What is Elmiron?
Made from Pentosan polysulfate (PPS), it is a medication used for interstitial cystitis and osteoarthritis. It is a semi-synthetic polysulfated xylan used either by mouth or in the bladder.
Problems Reported
Apparently last year Nieraj Jain, MD of Emory Eye Center in Atlanta, GA reported that a number of patients on Elmiron for many years had developed concerning changes in their macula—the central part of the retina responsible for delivering clear and central vision reported Specialty Medical Dialogues.
Kaiser Study
Based on reports such as the one from Emory Eye Center, medical investigators Robin A. Vora, MD, Amar P. Patel and Ronald Melles, MD Ophthalmologist from Kaiser Permanente conducted a study based of 4.3 million patients in the Kaiser Permanente database.
They found 140 patients taking an average of 5,000 pills annually over a 15 year period. 91 of the 150 agreed to participate in the study. The physicians conducted extensive analysis taking detailed images of the back of their eyes. Out of the 91 patients, 22 evidenced clear sign...

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