Israeli Health Payor Study Reveals Pfizer mRNA Vaccine Effectiveness Wanes Greatly for 60+ at 4.8 Months

A recent study led by Leumit Health Services and the Shamir Medical Center Institutional Review Board in Israel led to some concerning results. The study authors recently uploaded the manuscript to the preprint server medRxiv. Involving 33,943 fully vaccinated adults administered the Pfizer-BioNTech vaccine, three cohorts based on age were studied, including 1) 60 and up, 2) 40 to 59, and 3) 18 to 29. The study authors found concerning risk of breakthrough infection in those vaccinated at least 146 days (4.8 months) before reinfection—the risk further escalates for people older than 60. 

The Challenge

A growing number of breakthrough cases now occur with the delta variant of interest. As the variant has a far greater viral surge, this could be why vaccinated individuals succumb to COVID-19 infection. Yahoo News reported that, according to a leaked CDC document, there were approximately 35,000 symptomatic COVID-19 infections  per week among the fully vaccinated, but this needs to be confirmed.

Although most vaccinated cases don’t lead to severe cases, a growing trend in Israel reveals vaccinated people are at ever greater risks. To date, about...

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