Note that views expressed in this opinion article are the writer’s personal views and not necessarily those of TrialSite.
We are constantly reminded wash our hands with soap or alcoholic solutions that kill the coronavirus. But the coronavirus does not live on hands. COVID-19 starts in the upper respiratory tract (URT). The largest load develops in the nasopharynx. From there, it spreads into the lungs through the pharynx mucosal surfaces. Therefore, it stands to reason that we should frequently cleanse the upper respiratory tract: nasal cavity, oral cavity, nasopharynx, and oropharynx. The most promising antiseptic is Povidone-Iodine (PVP-I), because it has been used for this purpose in dentistry and otolaryngology for decades.
PVP-I is active against a broad spectrum of viruses, bacteria, and fungi. Before COVID-19, it was found effective against influenza viruses, common cold coronaviruses, SARS and MERS. No repurposing is needed. Recent trials have confirmed its safety, useability, and efficacy against SARS-COV-2.
Simultaneous mouth rinsing, gargling, and nasal drops of PVP-I, performed a few times daily, provides three benefits: prophylaxis (killing any virus that m...
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