Hoag First Hospital in Orange County to Enroll Patients in NK Cell Therapy Clinical Trial for Triple-Negative Breast Cancer Patients

Hoag First Hospital in Orange County to Enroll Patients in NK Cell Therapy Clinical Trial for Triple-Negative Breast Cancer Patients

Hoag Memorial Hospital Presbyterian today announced that it met a key clinical trial milestone,  enrolling the first two patients in a clinical study evaluating “Natural Killer,” or NK, cell therapy in women with triple-negative breast cancer. Hoag is the first and only site in Orange County enrolling patients in the study.

The Study

The phase1/b2 open-label study will evaluate the safety and efficacy of a combination of chemo-immunotherapy with “Trodelvy,” a low dose chemotherapy, in combination with Culver City, Calif.-based ImmunityBio’s Anktiva receptor agonist, and NK cell therapy, a type of immunotherapy. Participants are triple-negative breast cancer patients who have at least two prior treatments for metastatic disease. Treatment will continue for up to one year.  

Cell therapy involves modifying immune cells to recognize – and kill – cancer. Hoag is involved in a variety of cell therapy trials evaluating “natural killer,” or NK cell therapy, which has proven to be beneficial in treating solid tumors.

Hoag Director Comments

“Metastatic triple negative breast cancer patients often have a poor prognosis and high cancer recurrence rates and short duration ...

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