Hidradenitis Patients at Risk for Non-Alcoholic Fatty Liver Disease (NAFLD) Finds New University Hospital Marques DE Valdecilla Study Results

Hidradenitis Patients at Risk for Non-Alcoholic Fatty Liver Disease (Nafld) Finds New University Hospital Marques DE Valdecilla Study Results

A new study led by researchers at the University Hospital Marques de Valdecilla, published in the Journal of the European Academy of Dermatology and Venereology reports that hidradenitis suppurativa patients are at greater risk for having NAFLD.

The Study

A case-control study, the principal patients were recruited from a Spanish hospital. A total of 86 patients with HS and matched control were examined for body heights and weight, body mass index, abdominal circumference measurements at baseline.

Results

As reported in the Dermatology Advisor, patient examinations evidenced a high prevalence of NAFLD in patients with HS vs. controls (72.9% vs. 24.7%, respectively; P<.001). Compared with patients with HS and without NAFLD, those with HS and NAFLD were more obese; had higher abdominal perimeter as a marker of central adiposity (mean, 82.47 cm vs. 102.37 cm, respectively P<.001); and fulfilled in a higher proportion of metabolic syndrome criteria (5.3% vs. 49.0%, respectively; P<.001). Patients with HS and NAFLD had higher NAFLD (6.8±5.5 vs 4.9±1.9 KPa, respectively; =.03). The multivariable regression analysis found an independent association between HS and the presence of NAFLD (odds ratio, 7.75; CI, 2.54-23.64; P <.001), reports the Dermatology Advisor’s Brandon May.

Conclusion

The results show a high prevalence of NAFLD in HS patients independent of classic metabolic risk factors. Therefore, we suggest HS patients to be evaluated for NAFLD and managed accordingly.

Lead Research/Investigator

M.A. Gonzalez-Lopez, University Hospital Marques de Valdecilla-[email protected]