Hartmut Ehrlich and Philippe Pouletty discuss Abivax Clinical Programs Involving Covid-19 and more.

Hartmut Ehrlich and Philippe Pouletty discuss Abivax Pipeline of Clinical Programs involving Covid-19, Ulcerative Colitis, Crohn’s Disease and more.
https://www.abivax.com/pipeline/

 

– #COVID-19
https://www.abivax.com/pipeline/abx464-for-covid-19/
Ongoing Phase 2b/3 trial with ABX464 in Covid-19 (miR-AGE trial), the unique properties of the lead candidate (antiviral, anti-inflammatory, tissue repair) to treat elderly and high-risk Covid-19 patients, the rial is ongoing in Europe and Brazil (Mexico, Peru and Chile to follow shortly)

-#Cancer
https://www.abivax.com/pipeline/abx196/
ABX196 has been developed as a synthetic agonist of iNKT cells from a proprietary platform technology that identifies agonists of these types of cells that demonstrate immune enhancing effects in cancer models.
Preclinical data showed that ABX196 enhanced anti-tumoral activity when used alone and in combination with anti-PD1 antibodies or doxorubicin.

– Ulcerative Colitis
https://www.abivax.com/pipeline/abx464-ibd-uc/
ABX464 in Inflammatory Bowel Diseases (Abivax development priority), excellent two-year efficacy and safety data for ABX464 ulcerative colitis Phase 2a maintenance study and ongoing ulcerative colitis Phase 2b trial in 15 countries, the US and Canada

– Crohn’s disease
https://www.abivax.com/pipeline/abx464-for-crohns-disease/
Planned pivotal Phase 2b/3 trial with ABX464 in Crohn’s disease (FPI Q1 2021) and ngoing clinical trial with ABX464 in rheumatoid arthritis in 5 European countries

– HC
Ongoing clinical trial with second molecule, ABX196, in patients with hepatocellular carcinoma in the US

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