Xlear, and other anti-viral nasal sprays

  • Xlear, and other anti-viral nasal sprays

  • under_opinionated

    September 3, 2021 at 7:01 pm

    With both vaccinated and unvaccinated individuals being potential asymptomatic carriers for SARS-COV-2, and an absence of daily antigen testing, is it time to start considering anti-viral nasal sprays as a means of curbing the spread? It seems to me that commercially available sprays like Xlear should be talked about more? https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/2768627

  • Vicknaird

    September 3, 2021 at 9:48 pm

    Yes, definitely. Keeping Covid from taking up residence in the sinuses seems important and an important part of FLCCC I-MASK+ and I-MAST protocols. A neighbor put me on to XLEAR in the spring. I continue to use It whenever I go out. Plus it works without irritation. I understand that there was a study but haven’t followed up. I also wonder whether nebulized H2O2 might be useful, especially if breathed with a mask to hit lungs and nasopharyngeal area. Mercola DO, Shallenberger MD and others have promoted it— both suggest 5 ml (cc) 3% food grade H2O2 in 100 ml sterile saline yields 105 ml of 0.15% H2O2 solution with a 12 month shelf life in the fridge. Shallenberger recommends 3 ml every hour at first symptoms day 1 and then 4-6 times a day until symptoms cease. He uses it for all upper respiratory diseases. I have read short articles proposing this as an adjunct treatment for Covid, so I have some ready to go. Asked my DO about it. Thought it made sense, but knew nothing about its use. I’m droning on…


    David V

  • Vicknaird

    September 3, 2021 at 10:12 pm

    Feel I must add a plug for nigella sativa oil/seeds. See http://www.c19ivermectin.com for a number of studies showing efficacy against Covid (select More along top banner) I used it last fall/winter as prophylaxis. The Koshak et al study used 2, 500 mg caps of oil containing 0.7% thymoquinone (the active ingredient) a day to great effect. That’s only about 7 mg a day. The actual product they used in the study is readily available online: Marty’s Cuminmar black oil capsules, 150, 500 mg for about $35. Toxicity of thymoquinone is apparently extraordinarily low. I wonder if it’s action is dose dependent. Hard to compare studies because thymoquinone concentration not always evident. There are products online claiming to deliver 50 mg thymoquinone per ml oil, so possibilities abound. Nigella Sativa is not on FDA’s radar… yet.


    David V

  • Square-James

    September 4, 2021 at 12:27 am

    I have purchased Betadine Cold Defense nasal spray last month.

  • AndisSho

    September 5, 2021 at 6:53 pm

    Try to get things as benign to your biome as possible, or protocols that include “restoration times” for it to re-grow.

    Our little friends gnaw away pathogens like pollen and viruses. This is half of the effect of xlear.

    As xylitol strengthens or little friends, they can even drive out harmful bacteria causing new allergies. So it is no only anti-allergic by engulfing pollen or viruses in a film, but also prevents allergies from rising by prebiotic effects.

    We use DIY 0,13% iota-carrageenan sometimes with 9% xylitol added.

    (I like to try amentoflavone containing liquid plant extracts to replace grape seed extract, the clever stuff (that I have bought for the “original” recipy).

    If you have experience with micro destillation of etheric oils of plants, tell me.

    Pollen: 20% of R-Value linearly with 0..500Pollen/m³ !

    See https://t1p.de/le2q and paper


    So Film built-up sprays engulfing pollen and viruses should be demanded by state just like masks due to this paper! (and now do multiply a factor of est. 3x on the 20% by :

    mould (walls, A/C, humidifiers badly built or maintained, use wetted cloth),

    household dust, allergies/intolerances on pollen, food, (food) chemicals, etc., dry air, alcohol, cigarettes smoke, high CO2, …

  • Square-James

    September 6, 2021 at 4:41 pm

    FLCCC has published information about the use of 1% Providone Iodine nasal-oro irrigation to treat COVID.

    • AndisSho

      September 23, 2021 at 6:38 am

      According to Prof. Zastrow, gargling works but keep dose low. He uses1ml of 75mg/ml PVP-I mouthwash or gargle solution plus 1-2ml water.“Every third day before going to bed, do 40secs mouth rinsing (move it in mouth for saliva glands), then 40secs throat gargling.Spit it out, perhaps a second time as well.”(We get povidone-iodine for 3€/0.1L, so nearly a year per person)
      He says a working virucidal (as compared to mouthwash solutions in supermarket shelves) reliably inactivates viruses by diffusing into the insides of the dead mucosal cells comprising the derma, and prophylactically, every third day and only mouth and throat as starting place of infection (20%/80% ca.) is enough, since the cells need 5-6 days – incubation period – to grow from the dividing living base to the top where they shall dissolve to release mucilage load and build the mucosal slime barrier.
      If infected, upon dissolving they release a lot of viruses that only then can diffuse on the mucosa and reach all airways parts, from nostril till lungs. So if they are inactivated, no harm is done. He says no infectious amounts can be shed by diffusion through all the layers of mucous cells alone, not enough to infect the lungs or other persons.
      If symptoms do occur, one could call it break-through infection, do the 7x per day gargling and add virucidal nasal spray, like combo (Azelastine OR CPM anti allergic entry-inhibitors, both as well inhalable by nebulisers for lungs) AND (carrageenan OR Xylitol+GrapeSeedExtract), which make perfect sense to protect olfactory conk and brain. And lungs if you like.
      (Even iota-carrageenan has a non-clinical safety study including inhalation.For Xylitol: Do inhale only pure xylitol, up to 15%, like protocols for mucoviscidosis patients suggest, as I’m not sure how many patients would react to grape seed extract in lungs, I can not find a safety study for inhalation on this. Till then I state not to inhale, though I sometimes breath in quite deep upon spraying to mouth, which is the way if you are out and the lungs need care.)
      There are reports that in rare cases of multiple times per day and prolonged periods gargling and nasal spraying of iodine one could ingest too much iodine, TSH complaining…
      If you adhere to the above protocol, and do not swallow the gargle, you stay safe. If you are a 0 iodine patient, find a replacement. Sorry. Not yet sure what to choose.
      I still think that a lot of rare side effects are digged out by the vax trolls not wanting us to do prevention…History repeating. (While still no trial is found to measure D-dimers and other immune regulation and autoantibodies indicating parameters are drawn from blood before and after vaccination.)
      Prof. Zastrow said if you do not swallow it, the resorbed amount is negligible and he sees no problem even for low-on-iodine patients, but of course one can switch to alternatives the dental doctors sure know of. I’m still researching. Because the demand is total inactivation by diffusion insides the dead cell layers, I do not want to draw hasty conclusions like chlorine or h2o2 or any other of the long list, that probably ALL work…
      (Of course the reproducing base will continue to produce viral units in infected. If not released by dissolving, very mild course is warranted. On symptoms, he lets his patients gargle 7x/day, plus nasal spray you like.)
      I would like to use alcoholic extract from artemisia annua in xylitol as gargle.Dosing could be really low there, like 10drops in 100ml ;)As dosing for oral treatment of systemic treatment of COVID is also quite low, like 2-3ml.
      We need sponsors to do in-vitro viral load measurements of gargling infected persons.Per Test, we pay something like 60€, I heared.Only few test e.g. in the morning after gargling before sleeping, are needed.
      PCR etc. is quite useless here except to document reduction in number of infected cells over the days, as it counts inactivated viruses as well.

      One link is cool, as no one can say Saline water is harmful or deprive us from it:https://www.medrxiv.org/content/10.1101/2021.08.16.21262044v2
      It found factor 19x less hospitalisation (!!!) upon nose rinsing with saline water as very early treatment. It also compares to adding some PVP-I seemingly not changing it much, 1 less or so. Not statistically significant. But look at the frequency of treatment. In the Ratio that an effective treatment also always shows potential in prevention, upon adjusting frequency and dosing of a means when turning the gold medal from treatment to prevention, and together with the rationale of prevention to concentrate on throat and mouth, I would dare to say we can do prevention with salt water mouth rinsing and throat gargling. Done. Still I would do it rather 4-5x a day than every third day.

      Just to amuse you:On the contrast, you can read the Cochrane’s analysis on gargling PVP-I: “we excluded (long list) because of (not perfect for our high demands); we included: no studies.” — None left.So hilarious again. See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188293/pdf/CD013628.pdf#page13
      Stay safe and gargle.
      By the way, in summer, we only sprayed iota carrageenan DIY spray in the mouth to throat while breathing in on our kids to let them have some immune system training, via the nasal route, as work-out. It worked out well on a summer flu and a cold. Perhaps they sprayed a bit sloppy as well…Still two of them aspired droplets on different occasions this year, due to pulling up the nose (the sinusitis prevalent ones, short sniffs may be ok, but it is always playing with fire), so we used Azelastine inhalation 3puffs till inhaled all of it, switch on only upon breathing in, off, hold breath, release, repeat, 2 times on a day, and immune system took over again. For the new COVID for elder ones this will not happen so fast, so one would have to inhale much longer, like 10 days. Ask your pulmologist.
      Here we would need bead-LAMP RtLAMP.org with a mucosal DNA channel and calibrated. Load is viral units per dna units. Then you can observe mouth viral load versus throat viral load going up upon infection on any organs including lungs, for 40cents for the two tests, in 45mins., so you do not have to do CT etc..
      I think that antiviral inhaling, entry inhibiting or directly antiviral, is essential for outpatient treatment, because it is so effective.Add Hyaluron and panthenol Inhalation (for us bebanthen eye drops) – if pulmonologist concedes – very early as well. Keep up up to 2-3 months 2x/day for recovery as needed. Seehttps://link.springer.com/chapter/10.1007%2F978-3-642-23056-1_17

  • keaaw

    September 7, 2021 at 3:16 am

    FLCCC also mentions Scope and Listerine (with Thymol, Eucalyptus, and Menthol) as highly effective anti-covid washes, but I didn’t see any references supporting this, does anyone know of such references?

  • Square-James

    September 7, 2021 at 2:48 pm

    I have purchased supply from Amazon so that I will have the ability to make diluted Povidone Iodine solutions. I will test both the 1% solution and the 0.6% solution for nasal or throat irritability.

  • keaaw

    September 8, 2021 at 1:41 am

    This study reported thyroid dysfunction (clearing up 7 to 12 days after the trial completed) for povidone iodine usage, maybe they used too much? Maybe this means povidone iodone can’t then be for ongoing prophylactic use?


    • Square-James

      September 8, 2021 at 3:46 pm

      In this study they used a mixture of 1% Povidone Iodine solution, and 10% Povidone Iodine ointment, so I am not sure which concentration is the dominant one.

    • justamom

      September 9, 2021 at 8:38 pm

      After reading FLCCC’s recommendation, I’ve been mixing my own (cheap) Povidone Iodine (PI) nasal wash to use after being out in public. 2.5 ml of 10% PI mixed with 44ml saline nasal spray. I found specific information from this article: https://krcrtv.com/news/local/redding-doctor-says-he-may-have-a-solution-to-prevent-transmission-of-covid-19

      If I’ve done the math correctly, I think it ends up being 0.5% PI (half the 1% PI used in the nostrils from the jamanetwork study where patients had thyroid issues). Also, no where near 10% PI ointment in same study.

      BTW, found this study: https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E4E0EC39491A7284F40B01F0E77F2EA4/S0899823X20013562a.pdf/iodine-mouthwashes-as-deterrents-against-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2.pdf

      “Recently nasal and oral antiseptic formulations of PVP-I have
      been successfully tested in SARS-CoV2 with rapid, as short as 60
      seconds, inactivation capacity of at concentrations up to 2.5%. The safety profile of PVP-I applied to the nasal and oral cavity
      has been confirmed after >60 years of use and is addressed by a vast
      literature. Unlike other oral antiseptic agents, it does not cause
      irritation or damage to the oral mucosa, even after prolonged
      use. Although iodine absorption may occur in the long term with
      the use of PVP-I, thyroid gland dysfunction is rare. Moreover,
      despite its long-term use, the development of resistance to PVPI in microorganisms has not been reported.”

      The article referenced: https://journals.sagepub.com/doi/full/10.1177/0145561320932318

      “Povidone-iodine has been safely administered for up to 5 months in the nasal cavity and 6 months in the oral cavity. Concentrations less than 2.5% in vitro do not reduce ciliary beat frequency or cause pathological changes in ciliated nasal epithelium, upper respiratory, or mucosal cells. Adverse events with oral use have not been reported in conscious adults or children. Allergy and contact sensitivity is rare. Chronic mucosal use up to 5% has not been shown to result in clinical thyroid disease. PVP-I is rapidly virucidal and inactivates coronaviruses, including SARS-CoV and Middle East Respiratory Syndrome (MERS).

      Povidone-iodine can safely be used in the nose at concentrations up to 1.25% and in the mouth at concentrations up to 2.5% for up to 5 months. Povidone-iodine rapidly inactivates coronaviruses, including SARS and MERS, when applied for as little as 15 seconds. There is optimism that PVP-I can inactivate SARS-CoV-2, but in vitro efficacy has not yet been demonstrated.”

      Recently heard Dr. McCullough say something like a few drops of PI in juice-size glass of water for gargle and can dip Qtip in same solution and wipe inside nose.

      PI appears to be relatively safe in small concentrations for prophylaxis. I’m doing the cetylpyridinium chloride mouthwash though, to maybe avoid too much PI!

      • keaaw

        September 9, 2021 at 10:55 pm

        My question about PI is: the formulations I see on my local area are all are labelled as “for external use only” (including the one in the video on the KRCR TV link) and I’m concerned about the potential presence of additional ingredients that should not be inhaled even at a 2.5/44 dilution. The other ingredients I see in my locally available “Betadine”: glycerol, nonoxynol 9, citric acid, anhydrous, sodium hydrogen phosphate (disodium hydrogen phosphate), sodium hydroxide, purified water.

        “Although additional scrubs, solutions, swab sticks, and other PVP-I containing products are available in the 5% to 10% range, many contain additional salts, sudsing agents, and cosolvents that should be avoided in the nose and mouth. Most are specifically labeled for external use and carry warnings against exposure to eyes, ears, and mucosal surfaces. The chemical stability of PVP-I in aqueous solutions at room temperature declines with dilution, alkalinization, and contact with common low-density polymer packaging materials.” from: https://journals.sagepub.com/doi/full/10.1177/0145561320932318

        • justamom

          September 10, 2021 at 12:19 pm

          Yikes! I didn’t read that part. Maybe there is a surgical grade PI that you don’t get at Walgreens.

  • bgill876

    September 8, 2021 at 8:59 am

    I just purchased 2 bottles of nasal spray Enovid/Sanotize from a pharmacy in Israel for USD$45 each. Enovid has been approved in Israel as an OTC covid preventative and is currently in Phase 3 trial in Canada. Testing has indicated a 99.5% effectiveness of killing SARS-CoV-2.

  • Square-James

    September 17, 2021 at 8:40 pm

    I tried a self made 0.6% Povodone Iodine solution for nasal irrigation, and throat gargle.

    I poured 6 ml of 10% Povodone Iodine into a measurement beaker, and poured the content of that small beaker into a larger measurement beaker. I then filled up the larger measurement beaker with water to the 100 ml mark. The resulting 0.6% Povodone Iodine solution has a dark brown color in the beaker.

    Using the 0.6% Povodone Iodine solution for nasal irrigation and throat gargle resulted in a slightly stinging sensation in nasal tissue and in the throat. This stinging sensation went away after one hour.

    For comparison I have a generic antibacterial mouthwash that was not irritating when doing a throat gargle.

    • keaaw

      September 17, 2021 at 11:09 pm

      All the Povidone Iodine solutions I can find have other ingredients which are concerning: alcohols, salts, etc. There needs to be much more explicit direction on which one are safe, in what concentrations, dosing, and course of treatment.

      • Square-James

        September 18, 2021 at 6:36 pm

        Indeed, my 10% Povodone Iodine solution has these inactive ingredients: C12-13 Pareth-9, Citric acid, disodium phosphate, glycerin, sodium hydroxide, and water.

      • Square-James

        September 19, 2021 at 5:23 pm

        I did some additional study on the inactive ingredients. They are emulsifiers, preservatives, and for acidity adjustments. Povidone Iodine solution prefers to be stored in a slightly acidic environment. I believe a diluted Povidone Iodine solution will have a very short shelf life, because its PH will be nearly neutral from all that water dilution.

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