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Probably the best thing is this Bryant et. al. meta-analysis of 15 randomized controlled trials (RCTs) including >2000 patients which showed that ivermectin prevented the majority (62%) of COVID-19 deaths. Ivermectin deniers will probably bring up the retraction of the Elgazzar RCT which was included in this meta-analysis, but even after excluding the Elgazzar RCT, the remaining 14 studies still show that ivermectin prevented the majority of COVID-19 deaths, though the effect size drops just a little. Plus, several of these RCTs didn’t allow ivermectin’s full potential to be reached as they only administered a single dose, which is certainly not ideal but much better than no ivermectin; it’s highly analogous to insisting on only 1 mRNA vaccine dose to assess vaccine efficacy.
Unfortunately, a large fraction of the medical establishment is deeply biased against non-conventional therapies especially for deadly diseases, no matter what evidence exists. Pre-COVID, they held the same bias against the Vitamin C + thiamine + hydrocortisone sepsis protocol developed by Dr. Marik (FLCCC leader). A double-blind RCT published in JAMA which administered Vitamin C alone ignoring the other components still showed a large mortality benefit (though mortality remained much higher than the 5-10% that Marik observed at his own hospital using his exact complete protocol), so the deniers’ only argument was to keep repeating that mortality was not the “primary endpoint” of the JAMA RCT, as if that somehow changes the large mortality benefit that the RCT found.