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  • Horses and coronavirus

    Avatar IveyTech updated 5 days ago 1 Member · 8 Posts
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    April 18, 2021 at 3:01 pm

    <b itemprop=”name”>Horse antisera may be effective against COVID-19, says study

    The antisera — the blood serum containing antibodies — can be synthesised from the horse, and can be injected into humans infected with Covid-19 to neutralise the virus.

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    April 18, 2021 at 3:52 pm


    Yes, that’s fine and all as the FDA ignores it because it allows only ONE “therapeutic” EUA (and Remdesivir is occupying that slot). I would ask the FDA/HHS/NIH/CDC what sense does that make. There is the possibility that in the USA, medical doctors who are licensed to dispense and prescribe agents to patients with informed consent, can use “off-label” and repurposed drugs from veterinarian, nutritional and immune support categories without having the FDA approval.

    If ivermectin was not ever considered for EUA approval, it still is proven for horses, dogs, pigs, rats, cattle, fish and humans.

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    April 18, 2021 at 4:02 pm

    <div>🐎 The importance of the horse,as medical researchers stay in pursuit of a COVID-19 cure




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    April 18, 2021 at 4:07 pm


    “…Remdesivir is one of the antivirals currently being used with a limited
    window of action. As more drugs are being vetted, passive immunotherapy
    in the form of neutralizing antibodies can provide immediate action to
    combat the increasing numbers of COVID-positive cases. Herein, we
    demonstrate that equines hyper-immunized with chemically inactivated
    SARS-CoV-2 generate high titers of antibody with a strong virus
    neutralizing potential. ELISA performed with pooled antisera displayed
    highest immunoglobulin titer on 42 days post-immunization, at 1:51,200
    dilutions. F(ab’) 2 immunoglobulin fragments generated from the pools
    also showed very high, antigen-specific affinity at 1:102,400 dilutions.
    Finally, in vitro virus neutralization assays confirmed that different
    pools of F(ab’) 2 fragments could successfully neutralize SARS-CoV-2
    with titers well above 25,000, indicating the potential of this strategy
    in treating severe COVID-19 cases with high titers. The F(ab’) 2 was
    able to cross neutralize another SARS-CoV-2 strain, demonstrating its
    efficacy against the emerging viral variants and the importance of this
    approach in our efforts of eradication of COVID-19. In conclusion, this
    study demonstrates that virus-neutralizing antibodies raised in equines
    can potentially be used as a treatment regimen in the form of effective
    passive immunotherapy to combat COVID-19…”


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    April 18, 2021 at 4:27 pm

    If you give your horses a prophylactic, say Durvet brand Duramectin or Farnam brand IverCare 1.87% Ivermectin paste, for deworming twice a year, it can protect your horses from coronavirus, based on the real-world experience of people taking the paste for COVID-19 symptoms and improving their lung capacity and lowering the inflammation.

    If your horse has a coronavirus:

    “Coronavirus has been identified in the feces of healthy foals and those with intestinal disease. However, recent outbreaks of diarrhea and colic in adult horses are thought to be caused by coronavirus.

    Signs of coronavirus include:

    unwillingness to eat



    possibly abdominal pain (colic) and stool changes

    Occasionally, the disease worsens rapidly and leads to death (or euthanasia), but most cases resolve with supportive care (such as fluid administration and nutritional support). The diagnosis of coronavirus is made by identifying the virus in a horse’s feces.” -Merck manual

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    April 18, 2021 at 9:38 pm

    What Animals Can Get and Spread COVID-19?”



    “…Chimps and gorillas may catch COVID-19. Giant anteaters, bottlenose dolphins, horses, dogs, alligators, cats, sheep and Siberian tigers are also on the list of animals that may be able to catch and transmit the deadly pandemic coronavirus.

    These are conclusions from the team at University of California Davis who conducted a genomic analysis of dozens of species with an eye toward classifying coronavirus transmission risks between animals and humans and protecting endangered species in zoos and the wild.

    The study, published in the Proceedings of the National Academy of Sciences this month, looks at the 25 genes that code for the proteins of the ACE2 receptor. This is the cell membrane receptor with which the coronavirus couples to launch its reproduction cycle and thus initiates the infection…”

    “…A point of major and continuing concern is whether given appropriate circumstances, SARS-CoV-2 is capable of infecting horses and other domestic and wildlife animal species. At this point in time, there are no reports of the virus infecting or causing disease in horses nor is there any reason to believe that horses have a role to play in the transmission and spread of the virus.

    Isolated cases of SARS-CoV-2 infection have however been confirmed in other domestic species, specifically dogs and cats…”


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    April 18, 2021 at 9:46 pm

    Re:”What Animals Can Get and Spread COVID-19?”
    It is important to emphasise that SARS-CoV-2 is a totally distinct
    coronavirus from equine coronavirus or the coronaviruses that cause
    disease in the other domestic animal species. Furthermore, there has
    never been any indication since its original discovery that equine
    coronavirus has caused infection in humans.


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    May 2, 2021 at 4:29 pm

    April 27, 2021


    VINCOV-19 is obtained after immunisation of horses with inactivated SARS-CoV-2 virus in combination with adjuvants.

    Pre-clinical trials for VINCOV-19, which began in October last year,
    were highly successful, showing potent virus neutralising capability.
    The next phase of clinical trials will involve over 300 COVID-19
    patients spread across the country for examining the safety and efficacy
    of the antibodies. The clinical plan is to administer VINCOV-19 to
    patients with moderate to severe disease according to the published
    COVID-19 treatment guidelines as soon as they are detected positive.
    This reinforces the idea that the therapeutic strategy, with equine
    antibodies, will play a significant role in managing COVID-19 and the
    ensuing pandemic, said the press release.”

    Previous developments





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