Fluvoxamine: The Federal Government Should Invest in Research for Early Stage COVID-19 Treatment

Fluvoxamine The Federal Government Should Invest in Research for Early Stage COVID-19 Treatment

A common selective serotonin reuptake inhibitor and σ-1 receptor agonist, mounting data indicates that fluvoxamine prevents clinical deterioration in outpatients with acute COVID-19. This finding is based on the  peer reviewed published results from a clinical trial involving 152 study participants who were confirmed with SARS-CoV-2-based symptoms within 7 days of study participation. Led by Dr. Eric Lenze and a team from Washington University School of Medicine in St. Louis, the study results indicate yet another important opportunity for a repurposed therapy targeting COVID-19. Although the investigators acknowledge that broader determination of clinical efficacy would require more research, the team was able to demonstrate in this study a statistically significant difference in the fluvoxamine group versus the placebo over 15 days. While the U.S. government continues to invest billions into vaccines and novel therapeutics for COVID-19, data such as this should be triggering considerable activity, including the inclusion of fluvoxamine in the ACTIV-2 study as an example. TrialSite’s Daniel O’Connor was also able to connect with prominent fluvox...

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