European Study: Alpha Variant Likely Evading Vaccines Wreaking Havoc in Europe

Corresponding author Buqing Yi, PhD employed with the Institute of Medical Microbiology and Virology, Carl Gustav Carus Hospital in Dresden as well as colleagues from Max Planck Institute of Molecular Cell Biology and Genetics, Technische University DRESDEN-concept Genome Center and the Regional Public Health Authority for the city of Ústí nad Labem in the Czech Republic recently introduced the world to a likely vaccine evading SARS-CoV-2 Alpha variant wreaking havoc in parts of Europe.   A sub-lineage of the UK’s Alpha SARS-CoV-2 variant known as B.1.1.7, the variant is likely the culprit triggering huge surges in infections and possibly even the rising death rates in places such as Austria.  Not widely reported, this mutant was discovered by the initiative involving weekly genomic epidemiology analyses of SARS-CoV-2 samples collected from the border region between Germany, Poland and the Czech Republic. The novel B.1.1.7 sub-lineage includes mutations of nucleoprotein G204P and open-reading frame-8 K68 stop.  Now apparently this Alpha variant mutation represents the predominant variant in several European countries (e.g., Czech R...

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