Southwest Oncology Group (SWOG) reports that already depressed levels of patient participation in clinical trials may be further reduced by the presence of comorbid conditions. Many barriers exist to robust clinical trial participation—from physical barriers to onerous inclusion/exclusion criteria. SWOG reports that cancer patients with other illnesses or conditions, such as hypertension, asthma or a prior cancer, are less likely to talk with their health care provider about a cancer clinical trial. Additionally, they are less likely to be offered to join a clinical trial, and ultimately less likely to enroll in a trial. SWOG Cancer Research Network has produced a comprehensive study and can be reached at the link below.