CureVac Moves to Out-License Model Inking Deal Worth Nearly $600m with World’s Largest Privately-Held Pharma

CureVac Moves to Out-License Model Inking Deal Worth Nearly $600m with World’s Largest Privately-Held Pharma

The world’s largest privately-held pharmaceutical company, Germany’s Boehringer Ingelheim (BI), just inked a deal with cutting-edge mRNA vendor CureVac on an exclusive licensing and development collaborative deal. BI licensed CureVac’s CV9202, a novel investigational therapeutic mRNA vaccine in early clinical development for lung cancer treatment. Boehringer Ingelheim will start a clinical investigation of CV9202 in at least two different lung cancer settings, in combination with afatinib in patients with advanced or metastatic epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC) and in combination with chemo-radiation therapy in patients with unresectable stage III NSCLC. CureVac receives EUR 35 million (approximately $45 million). Furthermore, CureVac can achieve milestone payments of up to EUR 430 million (approximately $556 million) and royalties on sales.

Some Challenges

During the beginning of the pandemic, CureVac’s star was bright as the then POTUS invited the company’s CEO for a potential exclusive deal with Operation Warp Speed. They declined any exclusive to America and went on to progress COVID-19 mRNA-based candidate. Yet resul...

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