CHU Ste-Justine Evaluates Clinical Protocol Using Intranasal Fentanyl for Vaso-Occlusive Crisis in SCD Patients

Investigators from CHU Ste-Justine, Montreal Quebec, Canada noted vaso-occlusive crisis (VOC) is one of the most frequent causes of emergency visits and admissions in children with sickle cell disease (SCD).  Their recent study aimed to evaluate whether the use of a new pain management pathway using intranasal (IN) fentanyl from triage leads to improved care, translated by a decrease in time to first opiate dose. They embark on a retrospective analysis and validated the use of their developed protocol using IN fentanyl as first treatment of VOC in the Emergency Department by significantly reducing the time to first opiate and the number of IVs.

Lead Research and Investigator

Hugo Paquin, MD