A global team of influential researchers, clinicians, regulators, and citizen advocates suggest how we can start to build an evidence base for healthcare that is free of commercial influences. The landmark 2009 Institute of Medicine report identified widespread...
Transparency in Clinical Trials
Category
Reanalyzing Drug Trials in Depression and Chronic Pain with the Aim to Unearth New Data
Concerned that reports of clinical trials can exaggerate a treatment’s benefits and downplay its risks, two research groups will sift through data from tests of drugs involving thousands of people with chronic pain or depression. The question for those reanalyzing the...
Clinical Research Transparency and Lack Thereof: Does Publishing Lead to Credibility?
Researchers from Stanford, Harvard, London School of Economics and University of Ioannina School of Health Sciences came together to produce an analysis of the nature of and risks associated with unpublished clinical research. Large clinical trials that go unreported...
UK’s Dr. Aseem Malhotra & Sir Richard Thompson: Statin Side Effects Cannot Be Ignored Anymore
Prominent United Kingdom physicians are becoming increasingly vocal that almost half of patients taking statins have developed material side effects according to recent research, and recently covered in Express by Lucy Johnson. Recent Statin Study Reveals Significant...
University of Ioannina Finds a Great Number of Large Trials Not Publishing Results
University of Ioannina School of Health Sciences researchers found that a significant amount of large clinical studies are not reported, which could “threaten the credibility” of published clinical research evidence, according to the study which was published in the...
Lack of Transparency in Clinical Trials Results Harms Us All
Clinical trials are critically important to society. Our healthcare in many cases is at stake. In 2007, the United States Congress passed legislation requiring that clinical trial sponsors (commercial, academic, etc.) post clinical trial results on clinicaltrials.gov...
Why Are Major Medical Journals Failing to Report on Required Clinical Trials Results?
Jocelyn Kaiser, writing for Science Magazine, reports that major medical journals are not following their own rules for reporting clinical trials results. Ms. Kaiser followed the story of the Centre for Evidence-Based Medicine Outcome Monitoring Project (COMPare)...
Nordic Cochrane Centre Research Finds Commercial Sponsors’ Not Disclosing Influence
Recently reported in The BMJ, commercial sponsors are influencing trials’ analysis but may not always report on the full nature of their influence. A Danish group at the Nordic Cochrane Centre in Copenhagen undertook a comprehensive analysis of industry funding...