India’s Council of Scientific and Industrial Research (CSIR) seek creative ways to combat the novel coronavirus known as COVID-19. They suspect that Sepsivac—a commercial drug used for patients with gran-negative sepsis, may hold some promise. What is the angle with...
Sepsis
Cincinnati Children’s Hospital Investigators Develop PERSEVERE to Predict Mortality Levels from Sepsis
Cincinnati Children’s Hospital Medical Center investigators have developed a new rapid blood assay that can predict mortality risk levels from sepsis and could help inform precision medicine to treat the infections. They have filed patents through the institution’s...
University College London Hospitals Collaborates With Mologic in Major Clinical Trial for Early Sepsis Detection
University College London Hospitals (UCLH) and Mologic, Ltd, a UK-based diagnostic technology firm, are collaborating on a major clinical trial that evaluates the sponsor’s point-of-care (POC) diagnostic test for early sepsis detection. The Problem: Sepsis Detection...
University of Pittsburgh Big Data Research Reveals Hidden Subtypes of Sepsis
Much like cancer, sepsis isn't simply one condition, but rather many conditions that could benefit from different treatments, according to the results of a University of Pittsburgh School of Medicine study involving more than 60,000 patients. These findings, announced...
Cheetah Medical Successfully Completes Key Sepsis Clinical Trial
Cheetah Medical completed its enrollment for the Fluid Responsiveness Evaluation in Sepsis-associated Hypotension (FRESH) trial following successful primary outcomes. The FRESH study was led by Ivor Douglas, MD, FRCP, Denver Health Medical Center. It has enrolled...
University of Strathclyde Sepsis Diagnostic Technology Could Save Thousands of Lives in UK Alone
UK researchers from Glasgow Scotland’s University of Strathclyde as well as University of Leeds and Paisley’s Royal Alexandra Hospital report on sepsis test device that has the potential to save thousands of lives in the UK alone. Researchers from the Sepsis Trust...
St. Jude Identifies Method to Reduce Risk of Brain Damage in Leukemia Survivors
MDLinx reports that children with acute lymphoblastic leukemia (ALL) are at an extremely high risk of sepsis compared to the general population. In the first-published study of its kind, St. Jude Children’s Research Hospital scientists have discovered a link between...
Vanderbilt University Medical Center Research Fatal Toxicity with Immunotherapy Increasing
Pam Harrison of Medscape reports that Fatal toxic effects from immune checkpoint inhibitors (ICIs) are rare, but clinicians need to be aware of the diverse toxic effects that these drugs can have in as much as the use of these agents is rapidly increasing, a...
Patients with Sepsis Face Higher Risk of Stroke, Heart Attack Post Hospital Discharge
Patients with sepsis are at increased risk of stroke or myocardial infarction (heart attack) in the first 4 weeks after hospital discharge, according to a large study. Lead Research/Investigator Dr. Chien-Chang Lee, Department of Emergency Medicine, National Taiwan...
Harvard Designed CLOVERS Study Faces Challenges from Public Citizen
Consumer advocacy group Public Citizen has filed a complaint with the federal government to stop the Massachusetts General Hospital sponsored CLOVERS Study—see link for study. See the NPR Richard Harris article below summarizing the current situation: Public Citizen...
NIH Awards $500,000 to Study Sepsis Prevention
As reported in Loma Linda University website, Christopher Wilson, PhD, Associated Professor, Department of Physiology, and Lawrence D. Longo, MD Center for Perinatal Biology have received a $500,000 grant to study sepsis prevention through vagus nerve stimulation...