Gapapagos and Servier reported topline results from the phase 2 ROCELLA trial, which evaluated GLPG1972/S201086 versus placebo in treating patients with knee osteoarthritis. The trial failed to show efficacy over placebo. Additional analyses are being conducted to...
Rheumatology
Category
SOBI and Selecta Report Data from Phase 2 COMPARE Study of SEL-212 in Patients with Chronic Refractory Gout
Swedish Orphan Biovitrum and Selecta Biosciences reported topline data from the phase 2 COMPARE study, which evaluated the efficacy of SEL-212, a combination of Selecta's tolerogenic ImmTOR immune tolerance platform and a therapeutic uricase enzyme (pegadricase), to...
Northwell Health & the Feinstein Institutes for Medical Research One Step Closer to Groundbreaking Lupus Drug
Northwell Health’s Division of Rheumatology and The Feinstein Institutes for Medical Research announced today the results from the largest Phase 3 lupus nephritis clinical trial ever conducted. The study, known as the BLISS-LN trial, found positive results...
AbbVie Reports Novel Antibody Drug Conjugate ABBV-3373 Meets Endpoints in Phase 2 Study for Rheumatoid Arthritis
AbbVie announced positive data from a Phase 2 study of ABBV-3373, an investigational anti-tumor necrosis factor (TNF) Glucocorticoid Receptor Modulator (GRM) steroid antibody drug conjugate (ADC), in adult patients with moderate to severe rheumatoid arthritis....
AbbVie Announces Rinvoq (upadacitinib) Meets Endpoints in SELECT-PsA 1 Phase 3 Study in Psoriatic Arthritis
AbbVie announces positive results from SELECT-PsA 1, a Phase 3 study of Rinvoq compared to placebo and adalimumab in adult patients with active psoriatic arthritis who have a history of inadequate response to at least one non-biologic DMARD. The study met primary and...
Dr. Susan Manzi, MD,MPH with Allegheny Health Network a Globally Recognized Lupus Investigator
Dr. Susan Manzi, MD, MPH, with Allegheny Health Network, an internationally known lupus clinical researcher and investigator, was selected for the 2019 Distinguished Clinical Investigator Award by the American College of Rheumatology. Dr. Manzi is among an elite group...
Janssen Presents Positive Data from DISCOVER-1 and -2 Studies of Tremfya for Psoriatic Arthritis
Janssen presented positive data from the DISCOVER-1 and DISCOVER-2 Phase 3 studies, which were designed to evaluate the efficacy and safety of Tremfya for the treatment of adult patients with active PsA. These data were presented as part of an oral plenary session...
University of Newcastle Leads Study Revealing Four Versions of Sjögren’s Syndrome Leading to Potential Treatment Implications
Newcastle University researchers discovered that there are at least four versions of primary Sjögren's syndrome (PSS)—a chronic inflammatory disease that affects the parts of the body that produce fluids like tears and saliva. The studies revealed that the different...
FDA Grants Breakthrough Status for First-Ever Treatment for Lupus Nephritis Called Gazvya
The U.S. Food and Drug Administration granted breakthrough therapy designation of obinutuzumab (Gazyva) for lupus nephritis, major morbidity of systemic lupus erythematosus (SLE). Gazyva is a treatment for chronic lymphocytic leukemia. A monoclonal antibody, it blocks...
TRACE RA Study Indicates Statins Work on Patients Diagnosed with Rheumatoid Arthritis
The Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients with Rheumatoid Arthritis, or TRACE RA, recently published their findings in an issue of Arthritis & Rheumatology which is the official medical journal for the American...
Investigator Profile: MUSC Lupus Expert Gary S. Gilkeson
Gary S. Gilkeson, a distinguished professor in the Division of Rheumatology & Immunology at the Medical University of South Carolina (MUSCH) has been given the Master’s Designation—the American College of Rheumatology’s highest honor. Follow the Lupus News...
American College of Rheumatology Receives Grant to Help Increase Access to Clinical Trials
As reported in EurekAlert! the American College of Rheumatology (ACR) today announced the receipt of two, two-year grants from the Office of Minority Health (OMH) to support the development of programs that aim to increase the recruitment and enrollment in clinical...