Scientists at the University of California, San Francisco (UCSF) Quantitative Biosciences Institute (QBI) have worked in relative obscurity for many years delving deeply into how different classes and types of pathogen interact with human proteins; all in the hope of...
Protein
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The Clinical Trial Results Were ‘Beyond our Wildest Dreams’ as First Gene Therapy for Hemophilia in UK Works in Patients
A breakthrough gene therapy has enabled British medics to sustainably treat the most serious form of hemophilia. Patients that used to need to visit the hospital at least three times per week and were in constant mortal risk from even small cuts are now able to live...
Could A New Uncovered Protein & Virus Killer Support Vaccine & Therapy R&D?
Kings College and University College, London led a new study that identified a protein capable of killing viruses that form the missing clue to the natural antiviral mechanism of the body that can target the viruses based on their genetic patterns. Called KHNYN, the...
Research Team May Have Found a Way to Force Cancer to Self-Destruct
When mutated and overexpressed, MYC is a gene that drives tumor growth in multiple cancer types. Researchers have been on a mission to target this important gene but effectively achieving this goal has been a challenge. Now a University of Pennsylvania-led research...
Stanford Researchers Reveal Blocking Proteins Can Curb Memory Loss in Mice
New research from Tony Wyss-Coray and his collaborators reveals that older mice performed better on memory tests when a protein found on the walls of the blood vessels in the brain was blocked, reports Stanford. Although mice aren’t people, they become forgetful in...
Kezar Life Sciences Q1 2019 Report: Translating Immunoproteasome Research to Novel Therapeutic Approaches
Kezar Life Sciences recently summarized its Q1 2019 activities. Essentially a pre-revenue, publicly traded biotech venture based in South San Francisco, CA, as of this writing their share price is $20.27 for a market capitalization of $387.55 million. Based on...
University of Sydney Australia Study Evidences Muscle Protein Drinks Bad for Health
University of Sydney, Australia research reveals whey protein shakes from supplemental health stores may be bad for one’s health. They consist of whey proteins containing high levels of branched-chain amino acids (BCAAs). According to statistics in 2017, the global...
Roche Reports Proteomics Headed for Clinical Trials
Roche reports that technology that can take a snapshot of protein expression in tissue samples, already in use in drug discovery, could be applied to clinical trials. Roche also reports, according to PMLive, that it has been working with proteomics specialist...
UCSF Researchers Study How Cancer Tricks the Immune System
In a University of California, San Francisco research study, (published in the journal Cell) found cancer immunotherapy drugs hold great promise but still fall short for many desperate patients in need. The UCSF team is on to an explanation for why. Focusing on...
UC San Diego Health Research Finds Genome Wide Analysis Reveals New Pancreatic Cancer Strategies
University of California, San Diego Health researchers discovered an unexpected role of an immune system receptor—blocking it halts human cancer cell growth and improves survival in animal models reports Scott LaFee of University of California, San Diego Health. The...
Investigators on the Hunt to Find Gene Change Causing Alzheimer’s Disease
Researchers believe PSEN1 is involved in the production of the amyloid beta protein. When the gene is mutated, the protein isn’t trimmed to the best size, ends up longer and stickier and more easily forms plaques in the brain. A leading goal of Alzheimer’s treatment...
Gladstone Institutes Study Shows A New Culprit of Cognitive Decline in AD
A Gladstone Institutesled study finds blood protein destroys memory storage sites in the brain and may lead to new treatments. Led by Senior Investigator Katerina Akassoglou, PhD, Gladstone Institutes showed for the first time that a blood-clotting protein called...
Bioinformatics Analysis Leads to Identification of Hub Genes and Colon Cancer Outcome
As reported in Dovepress, Chinese research institutions collaborated on this insightful result. Research Institutions: State Key Laboratory of Cancer Biology National Clinical Research Center for Digestive Diseases Xijing Hospital of Digestive Diseases Air Force...
Prominent Research Team Finds Toxic Proteins’ Aggregation in the Brain Influence Alzheimer’s
Researchers from Ohio State University, Cambridge University (UK) and Columbia University Medical Center have identified in an Alzheimer’s research collaborative that a protein called tau is one of the main culprits in the disruptive process where toxic proteins’...
Northwestern University Study Human Protein to Combat Ebola Virus
Northwestern University researchers have found that the human protein RBBP6 is capable of fighting Ebola and could one day become an effective therapy to combat the deadly virus. The results of this important research were recently published in the Journal Cell...
Baylor Research Evidences Protein Connection to Cancer Growth
Baylor College of Medicine and Texas Children’s Hospital evidenced a correlation between mTORC1 and Src, proteins known to be hyperactive in cancer. Read the study in Nature Communications in the link. The study shows that Src is necessary and sufficient to activate...