Palm Beach Research Center, a Florida-based trial site organization, treated the first participant in a new AstraZeneca clinical trial investigating an monoclonal antibody combination treatment targeting COVID-19. Known as AZD7442, this investigational product is a...
Convalescent Plasma
Category
GC Pharma Gets Additional Nod for COVID-19 Plasma Therapy
Local hospitals are increasingly using GC Pharma’s GC5131, an investigational plasma therapy, to treat Covid-19 patients. The Ministry of Food and Drug Safety said it has granted two hospitals to use GC5131 for therapeutic purposes on Tuesday evening. The approval...
Johns Hopkins Leads COVID-19 Convalescent Plasma Project to Generate Greater Evidence
Johns Hopkins recently announced its National COVID-19 Convalescent Plasma Project, a clinical trial investigating the role of convalescent plasma in the potential treatment of COVID-19. Led by Johns Hopkins, participating researchers include Dr. Shmuel Shoham,...
Nuvance Health Hospitals Participate in National Convalescent Plasma Clinical Trial Sponsored by Johns Hopkins
Danbury and Norwalk hospitals, in addition to Vassar Brothers Medical Center in Poughkeepsie, all part of Nuvance Health, were selected by the COVID-19 Plasma Trial, sponsored by Johns Hopkins in partnership with American Red Cross and Bloomberg Philanthropies to...
Blood Drive: Plasma Pushes Ahead in COVID-19 Research and Practice
On August 25, Business Insider offered an overview of FDA’s authorization for convalescent plasma to treat COVID-19 while noting that, “some scientists worry it's too soon.” Back in 1918 during the Spanish Flu, doctors found, “they could treat sick patients with the...
PGIMER Led Convalescent Plasma Study: Convalescent Plasma Doesn’t Stop COVID-19 Disease Progression or Lower Mortality Rate
According to the results of the PLACID (PLAsma Convalescent InDia) trial, convalescent plasma in COVID-19 patients doesn’t forestall progression to severe disease or mortality. This study results from the Indian Council of Medical Research (ICMR) study in India. It is...
The PLACID Trial in India: Convalescent Plasma Offers No Benefit to Reducing Mortality or Disease Progression
A national multi-site clinical trial in India, funded by the Indian Council of Medical Research (ICMR), found that the use of convalescent plasma fails to reduce mortality or even stop progression of severe COVID-19. Conducted at 39 trial site organizations...
University of Rochester Medical Center Launches Two Convalescent Plasma Clinical Trials
The University of Rochester Medical Center (URMC) has initiated two clinical trials investigating the efficacy of using convalescent plasma as a therapy for 1) patients who have tested positive for COVID-19 but aren’t hospitalized and 2) individuals who have been...
Children’s Hospital of Philadelphia (CHOP) Study Reveals Convalescent Plasma Appears Safe for Children with Severe COVID-19 & Possibly Effective
Although to date no therapies have been proven effective for treating children with life-threatening complications from COVID-19 cases that possibly may change thanks to recent findings from a small study at Children’s Hospital of Philadelphia (CHOP). The study team’s...
University of Texas Health Science Center (Houston) Joins $8m Convalescent Plasma Study Funded by NIH
University of Texas Health Science Center at Houston (UT Health) recently received an $8 million grant from the National Institutes of Health to study the effectiveness of convalescent plasma with a randomized, double-blind clinical trial. This is part of a broader...
U.S. FDA Approved EUA for Convalescent Plasma Despite University of New Mexico Study Finding No Benefit
Although the U.S. Food and Drug Administration (FDA) recently awarded convalescent plasma emergency use authorization (EUA), investigators at the University of New Mexico (UNM) recently stopped a clinical trial earlier in the month after discovering no benefit to...
Update on the Use of Convalescent Plasma: Clinical Trial at Norton Healthcare
TrialSite has previously covered the news surrounding convalescent plasma; this includes the purported position that there was insufficient evidence that it reduces COVID-19 death rates, the move to halt its use by the FDA, and then the decision by the FDA to...
NBA Star Recovered from COVID-19, Donated Plasma & Now Asks Others to Contribute to Future Cures
NBA star Marcus Smart, the number 6 pick in the NBA draft back in 2014, has transformed into a defensive star on the world’s best professional basketball stage. Playing for the Boston Celtics, Smart survived COVID-19 and recently joined “The Fight Is In Us” campaign,...
The AstraZeneca Phase 3 COVID-19 Vaccine Study: Unprecedented Compression of Timeline of Est. Start Date to Est. Primary Completion Date
Is President Trump preparing to fast track the AstraZeneca COVID-19 vaccine known as AZD1222? According to a report in the Financial Times, this is exactly what is being contemplated as the administration would “bypass normal regulatory standards to fast-track”...
Trump Defies Fauci? Emergency Use Authorization Issued for Convalescent Plasma for COVID-19
On August 19, we first reported on the FDA’s decision to halt use of convalescent plasma for COVID-19. On August 21, we dug a bit deeper into the story; Mayo Clinic investigators were “puzzled” by the decision, and there is evidence that NIH Director Francis Collins...
Why Didn’t the HHS Consult with Mayo Clinic National Convalescent Plasma Officials in Moving to Halt the EUA?
Mayo Clinic investigators and supporting team members were “puzzled” by federal actions this week involved with at least the temporary halting of the convalescent plasma program. TrialSite summarized a New York Times article announcing that key federal research...
FDA Halts Use of Emergency Access of Convalescent Plasma as Therapy for COVID-19
The U.S. Food and Drug Administration (FDA) has halted the use of COVID-19 survivor’s convalescent plasma as a potential therapy for SARS-CoV-2 based on recent media reports, including the New York Times. Top public health officials have come together, including...
National Convalescent Plasma EUA Results: Not Sufficient Evidence for Claim that Convalescent Plasma Reduces COVID-19 Death Rate
National Convalescent Plasma EUA Results: Not Sufficient Evidence for Claim that Convalescent Plasma Reduces COVID-19 Death Rate TrialSite initially covered the National Convalescent Plasma Study, led by Mayo Clinic, with great enthusiasm. In fact, many...
Chinese Study: Use of Convalescent Plasma in Critically Ill COVID-19 Patients with Pneumonia can Worsen the Condition
A multicenter research team led out of China and including investigators from Brigham and Women’s Hospital as well as Harvard Medical School evaluated the clincial efficacy of convalescent plasma on critically ill patients with SARS-CoV-2, the virus behind...
The Need for Convalescent Plasma in TN
Research is proving convalescent plasma can help those that have COVID-19 recover faster. However, Ballad Health is having to outsource plasma from other regions due to a lack in local donations, but one Northeast Tennessee native is making the most of an unfortunate...