A clinical investigator from the University of Kansas School of Medicine, Patrick M. Moriarty, co-led a clinical trial testing a drug focusing on individuals who have inherited a condition subjecting them to high cholesterol irrespective of diet or lifestyle. The...
Cholesterol
Category
Experimental Drug Inclisiran Can Save 30,000 Lives Annually
Millions of people take daily statin pills to cut their cholesterol. Coming this year, a “ground-breaking” large-scale clinical trial will offer NHS patients a new form of medicine—gene silencing—in an injection called inclisiran. The NHS Health Secretary, Matt...
New Cardiovascular Drug on the Rise: ORION-10 & the Novartis $9.7 Billion Purchase
ORION-10 was the second of three 19-month Phase III clinical trials for inclusion for lowering cholesterol. Funded by sponsor The Medicines Company, a week after the sponsor announced the actual study data Novartis announced that it was paying $9.7 billion to buy the...
“Good” Cholesterol Found to Reverse Atherosclerosis in Mice with Diabetes
Researchers at the NYU School of Medicine perform study that “provides the ‘first direct evidence’ that raising levels of a simple, functional version of good cholesterol - the HDL protein shuttle that pulls cholesterol out of cells - reversed the progression of...
Atlanta VA & Emory Study the Connection Between High LDL Cholesterol & Early-Onset Alzheimer’s
Janice Wood of PsychCentral reports that new research has uncovered a link between high LDL cholesterol levels and early-onset Alzheimer’s disease. Based on these results, doctors could gain deeper insight as to how the disease develops and an exploration of potential...
St. Michael’s Hospital Meta-Analysis Finds Soy Protein Reduces LDL by 3-4%
St. Michael’s Hospital, Toronto, Canada sponsored a study recently as the U.S. Food and Drug Administration had plans to remove soy from its list of healthy foods for the heart. The Canadian researchers, via the St. Michael’s Hospital, conducted a meta-analysis of 46...
University of Nottingham Study Reveals Statins Don’t Work 50% of Time on Patients
The University of Nottingham, UK conducted a study suggesting statins are ineffective at lowering cholesterol to target levels in more than half of patients. Published in the journal Heart, the UK researchers found 51.2% of patients prescribed statins saw minimal...
Baylor Study of LDL Lowering Drug Found No Increase of Adverse Events
Baylor College of Medicine researchers took part in the CLEAR (Cholesterol Lowering via bempedoic Acid, an ACL-inhibiting Regimen) Harmony trial have found that while the new drug, bempedoic acid, where taken over approximately a year, did cause some adverse effects,...
Esperion Licenses Daiichi Cholesterol Drug for $300 Million
MarketWatch covered the up-to-date news of Esperion Therapeutics licensing out commercial rights in the European Economic Area and Switzerland for its experimental cholesterol-lowering therapy in a potentially $900 million deal with Daiichi Sankyo Europe (wholly owned...
PriceWatch: ODYSSEY Outcomes Trial Reveals Price of Alirocumab Needs to Come Down
As reported in Annals of Internal Medicine, The ODYSSEY Outcomes (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment with Alirocumab) trial included participants with a recent acute coronary syndrome. Compared with participants...