A group of major Chinese academic medical centers collaborated on basic research to identify non-small-cell lung cancer (NSCLC) biomarkers and small molecule drug candidates. The team understands that NSCLC remains a leading cause of cancer death. In the study they...
Chinese Research
The Wild East of Asian Research—Bioethics Experts Call for More Research Oversight in Asia
Eleven Media Group reports that four leading Chinese ethics’ scholars urge government authorities to tighten up scientific research oversight to mitigate growing risks involving unethical activities in clinical research. Published in Nature, the spark for more...
Chinese Research Shows Relationship Between Helicobacter Pylori and Expression of Programmed Death-1
Dovepress reports that at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, many studies have shown the programmed cell death protein 1 (PD-1) and its ligand, PD-L1, are expressed in advanced gastric cancer. Furthermore, detection of these...
First Affiliated Hospital Sun Yat-sen University, China Preclinical Stem Cell Research
BACKGROUND: Asthma is a chronic disease involving inflamed airways, which were previously demonstrated, can be modulated by the mesenchymal stem cells derived from induced pluripotent stem cells (iPSC-MSCs). However, the long-term effects of iPSC-MSCs in inflamed...
Chinese Gene Editing Firm Receives $10 Million Investment
Beijing-based EdiGene Inc. has raised an additional $10 million as part of a pre-B investment financing. Led by Green Pine Capital Partners, which focuses on biotech and other IP-rich investments, EdiGene is developing genome-editing technologies into therapeutics for...
Real-World Evidence and Chinese Experience
As the authors note, real-world evidence originates from a spectrum of studies that apply various epidemiological methods to data collected from real world settings. Real world data can be derived from a wide variety of sources from routine healthcare (electronic...
China Research Reveals Men Have Less Ability to Control Online Gaming Urges
A new study by Chinese researchers using medical imaging has found differences in the brain activity of men and women addicted to internet online gaming. The study was published in the International Journal Brain Imaging and Behavior. The researchers from Renji...
Investment in Medical Infrastructure Bolstering China’s World Position
The South China Morning Post reports that Mainland China has devoted 2.13 percent of its world’s second largest GDP to research and development in 2017—up from .8 percent in 1999. Hong Kong specifically is noticing a marked improvement in facilities and research on...
Generon Launches Phase I Trial of A-319 for ALL & B-cell Cancer Patients in China
China’s regulatory agency has approved the launch of Genron’s Phase I clinical trial to test its immunotherapy candidate, A-319, in patients with acute lymphoblastic leukemia (ALL) and B-cell lymphoma. A-319 is an antibody that binds the two targets at the same time:...
ESCO2 Gene Inhibits Tumor Metastasis Via Transcriptionally Repressing MMP2 in Colorectal Cancer
As reported in Dovepress, the following universities participated in this research: Department of General Surgery, Institute of Surgery Research, Daping Hospital, Army Medical University, Chongqing, China Department of Rheumatology, The Third Affiliated Hospital of...
Chinese Research Shows TRIM37 Targets AKT in Growth of Lung Cancer Cells
The following summary was reported in Dovepress: Shumin Dong,1 Xueqin Pang,2 Haijun Sun,3 Chunluan Yuan,4 Chuanyong Mu,5 Shiying Zheng6 1Department of Thoracic Surgery, The First Affiliated Hospital of Soochow University, The First People’s Hospital of Lianyungang...
The Clinical Trials Chinese Promise
China, the world’s most populous country, has the potential to become a leading research destination. As reported in The BMJ Opinion, prominent research authors articulate that attitudes toward China as research hub varies depending on point of view, ideology and...
China Makes Tremendous Progress with Diabetes
MedicalXpress reports that in the period of 1995 to 2015, China saw remarkable progress in diabetes research, according to a study recently published by Science China Life Sciences. During the past two decades, as China experienced unprecedented economic growth,...
Chinese Research: Breast Cancer Diagnosis Trigger for Diet & Lifestyle Changes
The most recent Dovepress report on research from Chinese academic medical centers centering on Chinese breast cancer patients, diet and lifestyle: Chinese breast cancer patients reported significant and long-term changes in dietary intake after cancer diagnosis,...
Clinical Outcomes of Patients with Depression Treated with Either Duloxetine, Escitalopram, Fluoxetine, Paroxetine or Sertraline
Dovepress reports that Duloxetine-treated patients had better 6-month outcomes in terms of depression severity and clinical and functional remission, compared with selective serotonin reuptake inhibitor-treated patients. Investigators included: Division of Mood...
Nuetraceutical Venture Partners with Jiangxi Government in China for Aging Research
ChromaDex Corp. (NASDAQ:CDXC), an integrated, science-based, nutraceutical company devoted to improving the way people age with its flagship ingredient NIAGEN® and consumer product - Wu Zhongqiong, Vice Governor of the People’s Government of Jiangxi Province,...
Using LC–MS/MS-Based Targeted Proteomics to Monitor the Pattern of ABC Transporters Expression in the Development of Drug Resistance
Doverpress reports on Chinese research: Purpose: The overexpression of ATP-binding cassette transporters (ABC transporters), mainly including permeability glycoproteins (P-gp), multidrug resistance (MDR)-related protein 1 (MRP1), and breast cancer resistance proteins...
Apatinib/Etoposide Promising in Platinum-Resistant Ovarian Cancer
Dave Levitan writing for Modern Medicine reports A phase II trial found that apatinib combined with etoposide offers promising efficacy in patients with platinum-resistant ovarian cancer. The regimen could offer advantages due to its home-based administration that...
Translational Research Center Established in Beijing
It is reported in Chinese news agency Xinhua that A research center, comprising of doctors from one of China's most famous hospitals and scientists from the country's top research organ, was set up in Beijing on Monday to enhance medical and health sciences. The...
Hydroxychloroquine and Risk of Development of Cancers
As reported in Dovepress: Background: Hydroxychloroquine (HCQ), one of the disease-modifying antirheumatic drugs, may lead to an inhibition of autophagy. Autophagy, an intracellular self-defense mechanism for the lysosomal degradation of cytoplasmic components such as...