Boston-based Dana-Farber Cancer Institute (DFCI) entered into a collaborative agreement with an Australian oncology-focused biotech called Kazia Therapeutics Limited (ASX: KZA; NASDAQ: KZIA) to investigate a drug called paxalisib (formerly GDC-0084) targeting primary...
Brain Cancer
Maryam Fouladi, MD, Named Co-Executive Director of Pediatric Neuro-Oncology Program
Maryam Fouladi, MD, has been named the co-executive director of the Pediatric Neuro-Oncology Program at Nationwide Children’s Hospital; and Rachid Drissi, PhD, will join the Center for Childhood Cancer and Blood Diseases in The Abigail Wexner Research Institute as a...
Hoag Hospital First in Nation to Conduct Innovative Antibody Brain Cancer Drug
Hoag Family Cancer Institute and Pickup Family Neurosciences Institute at Hoag, in collaboration with Nascent Biotech, Inc announced today a first in the nation clinical trial for a novel immunotherapy treatment that holds considerable promise for glioblastoma (GBM),...
Promising Interim Results for Investigational Combination Therapies Treating Newly Diagnosed Glioblastoma
The diagnosis of Glioblastoma, an aggressive tumor of the central nervous system, changes life as we know it. Upon the initial news and with the flurry of medical activity comes a recognition for those suffering with the cancer (and their loved ones) that life will...
Yale Cancer Center Study Indicates Pembrolizumab Might Extend Survival of Lung Cancer Patients with PD-L1 Biomarker
In a study funded by Yale Cancer Center and Merck, investigators learned that in about 25% of patients with an advanced form of lung cancer, it spreads to the brain. Thus far, the only way to combat such a situation is with radiation. However, consequences of such...
St. Jude Children’s Research Hospital has Identified a Novel Target for Medulloblastoma Brain Tumor
Investigators at St. Jude Children’s Research Hospital have discovered that the ABCC4 transporter is critical to the SHH signaling pathway in the brain tumor medulloblastoma. This work provides a rational for development of small molecule inhibitors that target ABCC4....
13-Year-old Girl with Severe Brain Cancer Supports Pediatric Cancer Research
Pediatric cancer research represents only 4% of all cancer research. This should change as many of our children fall to cancer. The dearth of funds flowing into pediatric cancer research is frankly, not acceptable. Nothing is more painful than to see our children go...
Michigan Medicine Joins PNOC to Expand Clinical Trials Access for Children High Risk Brain Tumors
Connecting young brain cancer patients with the most promising experimental therapies in the world is often a complicated and lengthy process with grave implications. These young children are on the radar of an elite global network of children’s hospitals have teamed...
Principal Investigator from Michigan’s Beaumont Health Receives $1.6M to Study Glioblastoma
Dr. Prakash Chinnaiyan, a Beaumont hospital radiation oncologist, has received $1.6 million from the National Institutes of Health (NIH) to study glioblastomas, the deadly brain tumors that claimed the lives of U.S. senators John McCain and Edward Kennedy as well as...
University of Bristol Pursues Brain Tumor Research to Help Move toward Precision Medicine
Brain tumors are the lading cause of death in children and adults under the age of 40, with 16,000 people in the UK diagnosed with a brain tumor annually. However, new research led by the Brain Tumour Research Centre at the University of Bristol in collaboration with...
The University of Birmingham with Ground-breaking Research Technique Assessing the Aggressiveness of Childhood Brain Tumors
About one-third of childhood cancer deaths in the UK result from brain cancers. The Brain Tumour Charity recently reported that the University of Birmingham, the clinical investigative site, developed a new personalized approach that can help clinicians give more...
University of Pennsylvania Investigators Progressing Glioblastoma Research with use of Tumor Organoids
Investigators at the University of Pennsylvania School of Medicine suspect that lab-grown brain organoids developed from a patient’s own glioblastoma may hold the answers on how best to treat this aggressive and very deadly form of brain cancer. These findings are...
UK’s University of Birmingham Study Leads Scan that Benefits Children with Brain Tumors
Thanks to a study led by an investigator at the University of Birmingham and Birmingham Children’s Hospital, UK, moving forward, children with cancer could be sparred unnecessarily aggressive treatments now that a new scan is available. This scan can predict how...
Mass General Hospital & Univ. of Florida Researchers On to New Strategy to Treat Deadly Brain Tumors
Massachusetts General Hospital (MGH) and University of Florida researchers study reveals a strategy that could make immune checkpoint inhibitors successful with glioblastomas—deadly primary brain tumors in adults. It involves the use of an investigational chemokine...
Australian Researcher Pursues Brain Cancer Cures—While His Own Daughter Nears the End
Dr. Matt Dun is a research with the University of Newcastle and Hunter Medical Research Institute with a focus on pediatric high-grade cancers. His research mission became far more intense and personal when he discovered his four-year old daughter Josie was fighting...
Mission to Combat Brain Tumors Starts with UK-based Brain Tumor Research
The UK’s Brain Tumor Research seeks to build the UK’s largest network of experts I sustainable brain tumor research in the quest to find a cure for this insidious class of disease. The organization showcases recent brain tumor research. The Cause Brain tumors are...
Roswell Park Comprehensive Cancer Center-Spinout Secures Deal in China Valued up to $148M
Roswell Park Comprehensive Cancer Center-Spinout Secures Deal in China Valued up to $148M. MimiVax represents an exciting opportunity in the Buffalo, NY area for the development of a cutting-edge cancer therapy. Targeting anti-cancer immunotherapy for the treatment of...
Barrow Neurological Institute Expanding in Downtown Phoenix a Neuro-Research Hub
The Barrow Neurological Institute team, a compelling organization focusing on medical research and innovation will be able to do more they broke ground for a new 130,050 square-foot research facility located adjacent to Dignity Health St. Joseph’s Hospital and Medical...
Inovio Reports Interim Results from Phase 2 Brain Cancer Study of INO-5401 Combined with PD-1 Inhibitor Libtayo (cemiplimab)
Inovio Pharmaceuticals announced positive interim results from a phase 2 study in patients with newly diagnosed glioblastoma multiforme (GBM) evaluating a combination of Inovio's INO-5401, a T cell-activating immunotherapy encoding for three tumor-associated antigens,...
Michigan State University Investigator Receives $2.1m to Study Existing Treatments for Select Rare Diseases
Michigan State University (MSU) College of Medicine investigator Bin Chen just was awarded $2.1 million by the National Institutes of Health (NIH) to scour vast databases of existing drugs in a quest to treat orphan diseases. The investigative team received an...